✦ LIBER ✦

Characterization of normal human cells by pyrolysis gas chromatography mass spectrometry

✍ Scribed by E. Reiner; L. E. Abbey; T. F. Moran; P. Papamichalis; R. W. Schafer

Publisher: John Wiley and Sons
Year: 1979
Tongue: English
Weight: 824 KB
Volume: 6
Category: Article
ISSN: 1076-5174
DOI: 10.1002/bms.1200061107

No coin nor oath required. For personal study only.

✦ Synopsis

Differentiation of normal human cells has been accomplished by pyrolysis gas chromatography mass spectrometry. Normal cells from human kidney, spleen, liver and brain tissues have been pyrolyzed and the products chromatographically separated and characterized by mass spectrometry. Molecular pyrolysis products giving rise to the characteristic pyro-mass chromatograms include, but are not limited to, alkenes, alkanes, nitriles and various ring compounds. Single ion mass chromatograms as well as multiple ion mass chromatograms have been used to explore the characteristic differences between various tissue materials. A dynamic computer methodology for comparing pyro-mass chromatograms has been developed for use in automatic identification and classification of the human cellular material.

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