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Characterization of Nerolidol Biotransformation Based on Indirect On-Line Estimation of Biomass Concentration and Physiological State in Batch Cultures of Aspergillus niger

✍ Scribed by Patrick J. Hrdlicka; Anders B. Sørensen; Bjarne R. Poulsen; George J. G. Ruijter; Jaap Visser; Jens J. L. Iversen

Book ID
109386853
Publisher
American Institute of Chemical Engineers
Year
2008
Tongue
English
Weight
155 KB
Volume
20
Category
Article
ISSN
8756-7938

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## Abstract This article describes a novel bioreactor configuration for production optimization of recombinant proteins in __Escherichia coli__. Inducer addition and harvesting are controlled on‐line based on indirect estimation of biomass concentration and specific growth rate from addition of NaO