Characterization of MTHFR, GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes in childhood acute leukemia
โ Scribed by Gunay Balta; Nazmiye Yuksek; Emel Ozyurek; Ulya Ertem; Gonul Hicsonmez; Cigdem Altay; Aytemiz Gurgey
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 73 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0361-8609
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๐ SIMILAR VOLUMES
Several polymorphic glutathione S-transferase enzymes are involved in the detoxification of active metabolites of many potential carcinogens from tobacco smoke and may therefore be important in modulating susceptibility to smoking-related cancers. As part of a hospital-based case-control study perfo
The authors established the genotype frequencies of cytochrome P450 (CYP1A1/MspI, CYP2E1/PstI, and CYP2E1/DraI), glutathione-S-transferase (GSTM1 and GSTT1), and p53 (exon 4/AccII and intron 3/16-base pair duplication) gene polymorphisms in cervical carcinoma patients and controls and evaluated the
thione-S-transferases. A high risk lung carcinoma group has been reported to have specific polymorphisms of the cytochrome P450 (CYP1A1) gene and the glutathi-