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Characterization of more than 85% of cystic fibrosis alleles in the Greek population, including five novel mutations

โœ Scribed by Maria Tzetis; E. Kanavakis; Thalia Antoniadi; Stavros Doudounakis; George Adam; Christos Kattamis


Publisher
Springer
Year
1996
Tongue
English
Weight
30 KB
Volume
99
Category
Article
ISSN
0340-6717

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Detection of more than 94% cystic fibros
โœ B. Mercier; W. Lissens; M. P. Audrรฉzet; M. Bonduelle; I. Liebaers; C. Ferec ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 449 KB

We have analysed 194 Belgian CF chromosomes using a variety of techniques: AF508 was detected by polyacrylamide gel electrophoresis; dot blotting of PCR products was used to identify the mutations G542X, 1717-1 G + A, and N1303K; molecular defects in exons 2, 3 , 4 , 5, 6b, 7, 11, 12, 13, 14a, 14b,