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Characterization of methylene diphenyl diisocyanate-haptenated human serum albumin and hemoglobin

✍ Scribed by Mhike, Morgen; Chipinda, Itai; Hettick, Justin M.; Simoyi, Reuben H.; Lemons, Angela; Green, Brett J.; Siegel, Paul D.


Book ID
121913881
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
712 KB
Volume
440
Category
Article
ISSN
0003-2697

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## Abstract High concentration glucose in diabetes mellitus may stimulate nonenzymatic glycation of proteins. Hemoglobin (Hb) and human serum albumin (HSA) are among the most sensitive proteins for the modification by glucose. In this paper, we report our study of Hb and HSA modification by glucose