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Characterization of metabolic activation of pentachlorophenol to quinones and semiquinones in rodent liver

โœ Scribed by Chin-Hsiang Tsai; Po-Hsiung Lin; Suramya Waidyanatha; Stephen M Rappaport

Book ID
114008699
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
328 KB
Volume
134
Category
Article
ISSN
0009-2797

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Rates of enzymatic single-electron reduction of some myotoxic quinones to semiquinone metabolites in an in vifro xanthine oxidase/hypoxanthine/catalase system varied widely. Naphthoquinones, especially juglone, were found to undergo rapid single-electron reduction. Benzoquinones and benzoquinoneimin