Characterization of melatonin binding sites in the Harderian gland and median eminence of the rat
β Scribed by M.A. Lopez-Gonzalez; J.R. Calvo; A. Rubio; R. Goberna; J.M. Guerrero
- Book ID
- 118345041
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 408 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0024-3205
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Vasoactive intestinal peptide (VIP) receptors and p-adrenergic receptors were investigated in rat Harderian gland membranes using '251-VIP and 125I-cyanopindolol(125I-CYP), respectively, as ligands. The receptor bindings were rapid, reversible, saturable, specific, and dependent on time, temperature
## Background: The Harderian gland (HG) is a tubulo-alveolar gland found within the ocular orbit of animals which present a nictitating membrane. The Harderian gland is regarded as an extrapineal melatonin producing organ and both, photoperiod and melatonin have been shown to exert an important ro