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Characterization of measles sequences from Pune, India

✍ Scribed by Niteen Wairagkar; Paul A. Rota; Stephanie Liffick; Naseem Shaikh; V.S. Padbidri; William J. Bellini

Book ID
102382509
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
82 KB
Volume
68
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

The goal of this study was to conduct the initial genetic characterization wild‐type measles viruses currently circulating in India. Reverse transcription‐polymerase chain reaction detected measles RNA in 11 of 14 throat swabs collected from sporadic and outbreak‐associated cases in the city of Pune, during 1996–1998. Sequence analysis of the H and N genes showed that six sequences were genotype D4, three were genotype D8, and two were genotype A. Continued virologic surveillance in other areas of India as well as neighboring countries will indicate the extent of genetic diversity present among wild‐type measles viruses circulating in India. J. Med. Virol. 68:611–614, 2002. © 2002 Wiley‐Liss, Inc.

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