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Characterization of Low-Affinity Binding Sites for Glibenclamide on the Kir6.2 Subunit of the β-Cell KATPChannel

✍ Scribed by L. Gros; A. Virsolvy; G. Salazar; D. Bataille; P. Blache


Book ID
115583636
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
70 KB
Volume
257
Category
Article
ISSN
0006-291X

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✍ David Moscatelli 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 834 KB

Scatchard analysis of binding of 125I-basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the presence of two binding sites: a high affinity site with KD of 20 pM and 80,000 sites per cell and a low affinity site with KD of about 2 nM and 600,000 sites per cell. The bind