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Characterization of Iodoxamic Acid and its Dimethyl Ester by Fast-Atom Bombardment Mass Spectrometry

✍ Scribed by Davide Pitrè; Maurizio Grandi; Pietro Traldi; Ron Self

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
243 KB
Volume
317
Category
Article
ISSN
0365-6233

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✦ Synopsis

Fast-atom bombardment mass spectra of iodoxamic acid, a contrast medium for cholecystocholangiography, and of its dimethyl ester are reported. Fragmentation patterns provide an unequivocal structural characterization of both compounds.

Die FAB-mPssenspektrometrisrbe

Charakterisierong der IodorPminsiiure und des entsprechenden Dimethylesters Die FAB-Massenspektren der Iodoxaminsaure, eines Kontrastmittels zur Cholecysto-cholangiographie, und ihres Dimethylesters werden besprochen. Die Fragmentierung erlaubt die eindeutige Strukturzuordnung beider Verbindungen. Iodoxamic acid (1)') [4,7,10,13-tetraoxahexadecane-l,16-dioyl-bis-(3-carboxy-2,4,6-triiodoanilide)] is one of the more widely used radiographic contrast media for intravenous cholecysto-

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