Insulin/IGF-1 hybrid receptors: Implicat
โ
Anne L. Frattali; Judith L. Treadway; Jeffrey E. Pessin
๐
Article
๐
1992
๐
John Wiley and Sons
๐
English
โ 622 KB
Classical insulin and IGF-1 receptors are azP2 heterotetrameric complexes synthesized from two identical a0 half-receptor precursors [I ,21. Recent data strongly suggests, however, that nonidentical ap half-receptor precursors can assemble to generate hybrid holoreceptor species both in vivo and in