Cultured hepatic stellate cells (HSCs), the cell type primarily involved in the progression of liver fibrosis, secrete insulin-like growth factor-I (IGF-I) and IGF binding protein (IGFBP) activity. IGF-I exerts a mitogenic effect on HSCs, thus potentially contributing to the fibrogenic process in an
Characterization of insulin-like growth factor binding proteins and regulation of IGFBP3 in human mesangial cells
โ Scribed by Grellier, Pascale; Sabbah, Michael; Fouqueray, Bruno; Woodruff, Kathleen; Yee, Douglas; Abboud, Hanna E; Abboud, Sherry L
- Book ID
- 109884374
- Publisher
- Nature Publishing Group
- Year
- 1996
- Tongue
- English
- Weight
- 829 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0085-2538
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