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Characterization of inhibitory effect of an anti-murine CD2 monoclonal antibody on the proliferation of T cell clones

✍ Scribed by Akihito Yokoyama; Hidehiko Suzuki; Tetsu Kamitani; Hideo Yagita; Ko Okumura; Saburo Yano


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
467 KB
Volume
28
Category
Article
ISSN
0165-2478

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Monoclonal antibodies (mAb) directed against the T cell differentiation antigen CD28 (Tp44) induce proliferation of resting T lymphocytes in the presence of phorbol esters. Moreover, it has been reported that such antibodies augment and sustain T cell proliferation induced by soluble antigens, phyto