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Characterization of IL-22 and antimicrobial peptide production in mice protected against pulmonary Cryptococcus neoformans infection

โœ Scribed by Wozniak, K. L.; Hole, C. R.; Yano, J.; Fidel, P. L.; Wormley, F. L.


Book ID
125512368
Publisher
Society for General Microbiology
Year
2014
Tongue
English
Weight
443 KB
Volume
160
Category
Article
ISSN
1350-0872

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We reported recently that interleukin (IL)-12 and IL-18 synergistically increased the fungicidal activity of mouse peritoneal exudate cells against Cryptococcus neoformans by inducing the production of interferon (IFN)-gamma by natural killer (NK) cells. To confirm these findings in vivo, we examine