Characterization of V642I-AβPP-induced c
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Takako Niikura; Marina Yamada; Tomohiro Chiba; Sadakazu Aiso; Masaaki Matsuoka;
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Article
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2004
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John Wiley and Sons
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English
⚖ 369 KB
## Abstract Amyloid precursor protein (AβPP), a precursor of amyloid β (Aβ) peptide, is one of the molecules involved in the pathogenesis of Alzheimer's disease (AD). Specific mutations in AβPP have been found in patients inheriting familial AD (FAD). These mutant AβPP proteins cause cell death in