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Characterization of Human Herpesvirus 7 U27 Gene Product and Identification of Its Nuclear Localization Signal

✍ Scribed by Kazuhiko Takeda; Muzammel Haque; Emi Nagoshi; Masaya Takemoto; Takuya Shimamoto; Yoshihiro Yoneda; Koichi Yamanishi


Book ID
112273031
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
255 KB
Volume
272
Category
Article
ISSN
0042-6822

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## Abstract BRD7, a novel bromodomain gene, is identified to be associated with nasopharyngeal carcinoma (NPC). Decreased or loss of expression of BRD7 was detected in NPC biopsies and cell lines. Overexpression of BRD7 could inhibit NPC cell growth and arrest cells in cell cycle by transcriptional