Characterization of human cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (hCTLA4Ig) expressed in transgenic rice cell suspension cultures

Targeting of interleukin-10 is superior

Targeting of interleukin-10 is superior to cytotoxic T-lymphocyte associated antigen 4 with human immunoglobulin G1 for the prevention of chronic allograft deterioration in organ transplantation

✍ Tao Xu; Cristina Haering; Chi-Keung Lau; Aiman Obed; Jian Ma; Axel Doenecke; Mar 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB

## Abstract ## Background Genetic manipulation of the allograft is an attractive approach to prevent the graft against chronic deterioration through stable expression of immunomodulatory or protective genes. However, the best strategy for prevention of chronic allograft deterioration remains uncle