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Characterization of human carbonic anhydrase XII stability and inhibitor binding

✍ Scribed by Jogaitė, Vaida; Zubrienė, Asta; Michailovienė, Vilma; Gylytė, Joana; Morkūnaitė, Vaida; Matulis, Daumantas


Book ID
118018495
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
457 KB
Volume
21
Category
Article
ISSN
0968-0896

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The nickel(II) derivative of carbonic anhydrase and its adducts with inhii itors have been investigated through electronic and nuclear magnetic resonance (mnrj spectroscopy. The metal ion in the pure enzyme is six-coordinated, and the\* is evidence for at least one water molecule in the coordination