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Characterization of Four Toxins from Buthus Martensi Scorpion Venom, which Act on Apamin-Sensitive Ca2+-Activated K+ Channels

✍ Scribed by Régine Romi-Lebrun; Marie-France Martin-Eauclaire; Pierre Escoubas; Fang Qi Wu; Bruno Lebrun; Miki Hisada; Terumi Nakajima


Book ID
115132505
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
999 KB
Volume
245
Category
Article
ISSN
1432-1327

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Solution structure of TsKapa, a charybdo
✍ E. Blanc; C. Lecomte; J. Van Rietschoten; J.M. Sabatier; H. Darbon 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 802 KB

TsKapa (TsK), purified from the Buthidae Tityus serrulatus is a very high potent ligand for small-conductance apaminsensitive calcium-activated potassium channels (SK). It is able to efficiently compete with apamin for binding on this channel (K 0.5 ‫؍‬ 0.3 nM) [Legros, C. et al., FEBS Lett. 390:81-