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Characterization of ERK1/2 signalling pathways induced by adenosine receptor subtypes in newborn rat cardiomyocytes

✍ Scribed by Renée Germack; John M Dickenson

Book ID: 110008144
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 316 KB
Volume: 141
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0705614

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## Abstract β‐Site APP cleaving enzyme 1 (BACE1) is an essential enzyme for the production of β amyloid. Since we found that injection of interferon‐γ (IFN‐γ) into young mouse brains increased BACE1 expression in astrocytes, we investigated molecular mechanisms underlying this process by cloning a