Lysophosphatidic acid (LPA) is a lipid metabolite that induces the activation of mitogen-activated protein kinase (MAPK) through binding to the G protein-coupled receptor in a number of cell lines and cultures. Recent studies have revealed that LPA is able to rapidly induce the phosphorylation of MA
Characterization of epidermal growth factor receptor in rat buccal mucosal cells
β Scribed by Wang Shoou-Lih; Chi Ying Wu-Wang; Amalia Slomiany; Bronislaw L. Slomiany
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 647 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0020-711X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The metabolism of the receptor for epidermal growth factor (EGF) in Aβ431 cells has been measured by labeling the receptor in vivo with radioactive amino acid precursors and then determining, by immunoprecipitation with specific antiβEGF receptor antisera, the rate of degradation of the
In the aged liver, cell proliferation and induction of DNA synthesis by epidermal growth factor is impaired. Changes in the hepatic handling of epidermal growth factor may be important for these effects. I compared epidermal growth factor handling in the livers of young and old rats. Epidermal growt
Multidrug-resistant human neuroblastoma cell lines obtained by selection with vincristine or actinomycin D from two independent clonal lines, SH-SY5Y and MC-IXC, have 3- to 30-fold more cell surface epidermal growth factor (EGF) receptors than the drug-sensitive parental cells as indicated by EGF bi