𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of drug purity by liquid chromatography

✍ Scribed by Sven-Olof Jansson

Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
511 KB
Volume
4
Category
Article
ISSN
0731-7085

No coin nor oath required. For personal study only.

✦ Synopsis

Applications of liquid chromatography (LC) in the characterization of drug purity are reviewed. Examples are given of the development of methods for the separation of impurities in acids, amines and neutral drug substances. A variety of methods and techniques are discussed including normal-phase and reversed-phase LC, gradient elution, and multidimensional separation systems.

πŸ“œ SIMILAR VOLUMES

Assay and purity evaluation of 5-chloroo
Assay and purity evaluation of 5-chlorooxindole by liquid chromatography
✍ Stephen T. Colgan; Gary R. Haggan; Robert H. Reed πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 488 KB

5-Chlorooxindole (5-CO) is a starting material for tenidap sodium, a pharmaceutical drug candidate produced by Pfizer. To insure potency and purity of the drug substance, it is necessary to demonstrate that commercial supplies of 5-CO are free from elevated levels of chemical analogs that could be c

Characterization of Botrytis by gasβ€”liqu
Characterization of Botrytis by gasβ€”liquid chromatography
✍ A.C. Thomas; J.M. KotzΓ©; F.N. Matthee πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 English βš– 436 KB

In recent years sophisticated techniques have been utilized for the rapid characterization of micro-organisms. Gas-liquid chromatography (GLC)la4, pyrolysis GLCsF7 and electrophoresis 8-1P have been applied in a search for more rapid and specific methods for identification purposes. With the increas