Characterization of DNA methylation change in stem cell marker genes during differentiation of human embryonic stem cells
β Scribed by Seungeun Yeo; Sangkyun Jeong; Janghwan Kim; Jee-Soo Han; Yong-Mahn Han; Yong-Kook Kang
- Book ID
- 116295066
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 357 KB
- Volume
- 359
- Category
- Article
- ISSN
- 0006-291X
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Embryonic stem (ES) cells are derived from the inner cell mass of blastocysts, and in response to retinoic acid (RA) are induced to differentiate to form some of the first distinguishable cell types of early mammalian development. This makes ES cells an attractive model system for studying the initi
## Abstract Temporal analysis in gene expression during differentiation of neural stem cells (NSCs) was performed by using inβhouse microarrays composed of 10,368 genes. The changes in mRNA level were measured during differentiation day 1, 2, 3, 6, 12, and 15. Out of 10,368 genes analyzed, 259 gene