Characterization of DNA isolated from metaphase chromosomes of cells containing Epstein-Barr virus
β Scribed by H. Ludwig; N. Biswal; M. Benyesh-Melnick
- Book ID
- 115744430
- Publisher
- Elsevier Science
- Year
- 1971
- Weight
- 498 KB
- Volume
- 232
- Category
- Article
- ISSN
- 0005-2787
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Immunologic studies of Epstein-Barr virus (EBV) have implicated EBV in undifferentiated and partially differentiated, non-keratinizing nasopharyngeal carcinoma (NPC). Patients with the well-differentiated, keratinizing form of NPC have EBV serologic patterns similar to those of control populations.
## Abstract ## Background Little has been known about whether EpsteinβBarr virus (EBV) could persist in nasopharyngeal carcinoma (NPC) cells by chromosomal integration, and no NPC cell line harboring integrated EBV has been reported. In this study, we explored this issue through isolating EBVβinfe