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Characterization of DNA fragmentation events caused by genotoxic and non-genotoxic agents

✍ Scribed by Jonathan E Ploski; Peter D Aplan


Book ID
114070305
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
537 KB
Volume
473
Category
Article
ISSN
0027-5107

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## Abstract DNA fragmentation and nuclear condensation are important nuclear changes in apoptosis. In this study we determined whether DNA fragmentation and nuclear condensation occur in astrocytes treated with 100–200 ΞΌM of the genotoxic agent __M__‐nitroso‐__N__‐nitroguanidine (MNNG). Our study a