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Characterization of Dkk1 gene regulation by the osteoblast-specific transcription factor Osx

✍ Scribed by Chi Zhang; Hui Dai; Benoit de Crombrugghe

Book ID
116303225
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
379 KB
Volume
420
Category
Article
ISSN
0006-291X

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## Abstract The Cbfa1/Runx2 is an important transcription factor necessary for osteoblast differentiation and bone formation. However, the signaling pathways regulating Runx2 activity are just beginning to be understood. Inconsistencies between Runx2 mRNA or protein levels and its transcriptional a