𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties

✍ Scribed by Carles Ferrer-Costa; Modesto Orozco; Xavier de la Cruz

Book ID
115631548
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
631 KB
Volume
315
Category
Article
ISSN
0022-2836

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

In silico prediction of deleterious sing
In silico prediction of deleterious single amino acid polymorphisms from amino acid sequence
✍ Shuyan Li; Lili Xi; Jiazhong Li; Chengqi Wang; Beilei Lei; Yulin Shen; Huanxiang πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 211 KB

## Abstract Molecular cause of human disease retains as one of the most attractive scientific research targets for decades. An effective approach toward this topic is analysis and identification of disease‐related amino acid polymorphisms. In this work, we developed a concise and promising deleteri

In silico functional profiling of human
In silico functional profiling of human disease-associated and polymorphic amino acid substitutions
✍ Matthew Mort; Uday S. Evani; Vidhya G. Krishnan; Kishore K. Kamati; Peter H. Bae πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 587 KB

An important challenge in translational bioinformatics is to understand how genetic variation gives rise to molecular changes at the protein level that can precipitate both monogenic and complex disease. To this end, we compiled datasets of human diseaseassociated amino acid substitutions (AAS) in t