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Characterization of Desamino-5-[125I]Iodo-3-Methoxy-Zacopride ([125I]MIZAC) binding to 5-HT3 receptors in the rat brain

✍ Scribed by William A. Hewlett; Sofyia Fridman; Bakula L. Trivedl; Denms E. Schmidt; Tomas De Paulis; Michael H. Ebert

Book ID
117449417
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
997 KB
Volume
22
Category
Article
ISSN
0278-5846

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## Abstract In an attempt to develop a specific probe of serotonin 5‐HT~3~ receptors, various methods have been investigated to synthesize a radioiodinated derivative of the potent 5‐HT~3~ antagonist zacopride. The direct iodination of 5‐dechloro‐zacopride 2 was performed using NaI in the presence