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Characterization of defective nucleotide excision repair in XPC mutant mice

✍ Scribed by David L Cheo; Hendrick J.T Ruven; Lisiane B Meira; Robert E Hammer; Dennis K Burns; Nancy J Tappe; Albert A van Zeeland; Leon H.F Mullenders; Errol C Friedberg

Book ID
114071250
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
486 KB
Volume
374
Category
Article
ISSN
0027-5107

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✍ Brian S. Thoma; Karen M. Vasquez πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 270 KB

## Abstract It has been reported that 80–90% of human cancers may result, in part, from DNA damage. Cell survival depends critically on the stability of our DNA and exquisitely sensitive DNA repair mechanisms have developed as a result. In humans, nucleotide excision repair (NER) protects the DNA a