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Characterization of Coumestrol, a Naturally Occurring Plant Estrogen

✍ Scribed by Bickoff, E. M.; Lyman, R. L.; Livingston, A. L.; Booth, A. N.

Book ID: 120351175
Publisher: American Chemical Society
Year: 1958
Tongue: English
Weight: 408 KB
Volume: 80
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja01548a043

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Mice bearing intrasplenic ovarian autografts were treated with coumestrol (500 pg/gm diet) and estradiol-17 /3 (0.5 &day) for 14 days. The splenic grafts of all controls were in various stages of follicular development, whereas some of those receiving estradiol and coumestrol became luteinized. The