Metallothionein-mediated cisplatin resis
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Paul A. Andrews; Michael P. Murphy; Stephen B. Howell
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Article
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1987
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Springer
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English
โ 638 KB
We have determined the ability of two human ovarian carcinoma cells to over-express metallothioneins (MTs) and the subsequent effect this elevation has on DDP cytotoxicity. Cells of 2008 and COLO 316 human ovarian carcinomas that were resistant to CdCl2 were obtained by stepwise selection and chroni