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Characterization of chromosome 12 anomalies in human germ cell tumors

✍ Scribed by R.F. Suijkerbuijk; R.J. Sinke; A.M. Meloni; J.M. Parrington; J. van Echten; B. de Jong; J.W. Oosterhuis; S. Castedo; L. Roque; G. Soares; A.A. Sandberg; A. Geurts van Kessel

Book ID: 119106261
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 92 KB
Volume: 77
Category: Article
ISSN: 0165-4608
DOI: 10.1016/0165-4608(94)90279-8

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## Abstract We present molecular data to demonstrate that the isochromosome 12p, specific for human germ cell tumors (GCTs), is of uniparental origin. Eight GCT‐derived cell lines, containing one or more copies of i(12p) and/or other 12p anomalies, were analyzed with different 12p‐derived polymorph