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Characterization of C/EBP Binding Sites Downstream of the Transcriptional Start Site in the HIV-1 LTR

✍ Scribed by Yujie Liu, Michael Nonnemacher, Aikaterini Alexaki, Brian Wigdahl

Book ID
120692856
Publisher
BioMed Central
Year
2005
Tongue
English
Weight
69 KB
Volume
2
Category
Article
ISSN
1742-4690

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## Abstract In human immunodeficiency virus type 1 (HIV‐1) latently infected cells, NF‐kappaB (NF‐κB) plays a critical role in the transcriptional induction of the HIV‐1 promoter. The __trans__‐activating ability of NF‐κB can be modified by another nuclear factor C/EBPΞ² that can physically bind to