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Characterization of Cdk955 and differential regulation of two Cdk9 isoforms

✍ Scribed by Sarah M. Shore; Sarah A. Byers; Paul Dent; David H. Price


Book ID
116507053
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
282 KB
Volume
350
Category
Article
ISSN
0378-1119

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## Abstract Cdk9, a member of the cyclin‐dependent kinase family, is the catalytic subunit of P‐TEFb, a protein kinase complex that stimulates transcriptional elongation. Cdk9, complexed with its regulatory partner cyclin T1, serves as the cellular mediator of the transactivation function of the HI