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Characterization of CD8+ T cell repertoire diversity and persistence in the influenza A virus model of localized, transient infection

โœ Scribed by Stephen J Turner; Katherine Kedzierska; Nicole L La Gruta; Richard Webby; Peter C Doherty


Book ID
116885354
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
150 KB
Volume
16
Category
Article
ISSN
1044-5323

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The mechanistic basis of memory T-cell development is poorly defined. Phenotypic markers that define precursors at effector stages have been characterized for acute systemic infections with high antigen load. We asked whether such markers can identify memory precursors from early effectors (d6) to l