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Characterization of CD4+ Single Positive Cells That Lack CD3 in the Human Thymus

✍ Scribed by Yukiyasu Takeuchi; Yoshitaka Fujii; Meinoshin Okumura; Keiji Inada; Kazuya Nakahara; Hikaru Matsuda

Book ID
112238782
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
287 KB
Volume
151
Category
Article
ISSN
0008-8749

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The transcription factor FOXP3 plays a key role in CD4 + CD25 + regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4 + CD25 + cells that express FOXP3 protein