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Characterization of Candida rugosa lipase immobilized onto magnetic microspheres with hydrophilicity

✍ Scribed by Yang Yong; Yong-Xiao Bai; Yan-Feng Li; Lei Lin; Yan-Jun Cui; Chun-Gu Xia


Book ID
108252681
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
738 KB
Volume
43
Category
Article
ISSN
1873-3298

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Lipase from Candida rugosa immobilized on a nylon support has been used to synthesize lovastatin, a drug which lowers serum cholesterol levels, by the regioselective acylation of a diol lactone precursor with 2methylbutyric acid in mixtures of organic solvents. Analogs of lovastatin having a differe