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Characterization of Calcium-Mediated Intracellular and Intercellular Signaling in the rMC-1 Glial Cell Line

✍ Scribed by Diana Yu; Marius Buibas; Siu-Kei Chow; Ian Y. Lee; Zakary Singer; Gabriel A. Silva


Book ID
107620649
Publisher
Springer
Year
2008
Tongue
English
Weight
535 KB
Volume
2
Category
Article
ISSN
1865-5025

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN