𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of bropirimine O-glucuronidation in human liver microsomes

✍ Scribed by Wynalda, M. A.; Wynalda, K. M.; Amore, B. M.; Fagerness, P. E.; Wienkers, L. C.

Book ID
111923280
Publisher
Informa plc
Year
2003
Tongue
English
Weight
276 KB
Volume
33
Category
Article
ISSN
0049-8254

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Identification and characterization of o
Identification and characterization of oxymetazoline glucuronidation in human liver microsomes: Evidence for the involvement of UGT1A9
✍ Mukesh K. Mahajan; Vinita Uttamsingh; Liang-Shang Gan; Barbara Leduc; David A. W πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 386 KB

The incubation of oxymetazoline, a nonprescription nasal decongestant, with human liver microsomes (HLMs) supplemented with uridine-5-diphosphoglucuronic acid (UDPGA) generated glucuronide metabolite as observed by LC/MS/MS. The uridine glucuronosyltransferases (UGTs) responsible for the O-glucuroni

Glucuronidation of olanzapine by cDNA-ex
Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes
✍ Kristian Linnet πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 72 KB

Olanzapine is a widely used, newer antipsychotic agent, which is metabolized by various pathways: hydroxylation and N-demethylation by cytochrome P450, N-oxidation by flavin monooxygenase and direct glucuronidation. In vivo studies have pointed towards the latter pathway as being of major importance