Characterization of blocked nucleosides by mass spectrometry. Benzyl derivatives
β Scribed by H. T. Cory; K. Yamaizumi; David L. Smith; D. R. Knowles; Arthur D. Broom; James A. Mccloskey
- Book ID
- 112125645
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1979
- Tongue
- English
- Weight
- 345 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-152X
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Geometric and positional isomers of the A\*-oxazoline ring system have been characterized by their mass spectral fragmentation patterns. The composition of the major ions in the spectra have been determined by high resolution mass spectrometry. A fragmentation pathway for the formation of these ions
## Abstract 4β²βAzaβ2β²,3β²βdideoxyerythrofuranosyl derivatives of thymine (AdT, **1**) and uracil (AdU, **2**) are analogues of 2β²,3β²βdideoxyribofuranosyl thymine (ddT, **3**) and uracyl (ddU, **4**). Compounds **1** and **2** are representative of a new class of antiviral agents where the sugar moie