Characterization of synthetic peptide by
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Seksiri Arttamangkul; Brian Arbogast; Douglas Barofsky; Jane V. Aldrich
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Article
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1997
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Springer Netherlands
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English
⚖ 744 KB
The cyclization of a linear dynorphin A (Dyn A) analogue to give the lactam derivative cyclo[D-Asp2,DapS]Dyn A(1-13)NH 2 (where Dap = c~,lS-diaminopropionic acid) was studied to evaluate the usefulness of different coupling reagents for side chain to side chain lactam formation. This cyclization pro