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Characterization of antigenic domains and epitopes in the ORF3 protein of a Chinese isolate of avian hepatitis E virus

โœ Scribed by Zhao, Qin; Sun, Ya-ni; Hu, Shou-bin; Wang, Xin-jie; Xiao, Yi-hong; Hsu, Walter H.; Xiao, Shu-qi; Wang, Cheng-bao; Mu, Yang; Hiscox, Julian A.; Zhou, En-Min


Book ID
123111781
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
702 KB
Volume
167
Category
Article
ISSN
0378-1135

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A recombinant subunit antigen (ORF2.1), representing the carboxy-terminal 267 amino acids of the 660-amino-acid hepatitis E virus (HEV) capsid protein, was expressed in Escherichia coli and used for the immunisation of rats. Purified antigen formulated with either Aluminium Hydroxide Gel Adjuvant (A