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Characterization of antibodies that selectively detect α-synuclein in pathological inclusions

✍ Scribed by Elisa A. Waxman; John E. Duda; Benoit I. Giasson


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
567 KB
Volume
116
Category
Article
ISSN
0001-6322

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To facilitate studies of the normal biology of ␣-synuclein, a member of a family of neuronal proteins of unknown function, and to elucidate the role of ␣-synuclein pathologies in neurodegenerative diseases, we generated and characterized a panel of anti-synuclein antibodies. Here we demonstrate that