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Characterization of an amino-terminal fragment of insulin-like growth factor binding protein-3 and its effects in MCF-7 breast cancer cells

โœ Scribed by Houta Salahifar; Sue M. Firth; Robert C. Baxter; Janet L. Martin


Book ID
117837074
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
273 KB
Volume
10
Category
Article
ISSN
1096-6374

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The mitogenic effects of insulin-like growth factors (IGFs) are regulated by a family of insulin-like growth factor binding proteins (IGFBPs). One member of this family, IGFBP-3, mediates the growth-inhibitory and apoptosis-inducing effects of a number of growth factors and hormones such as transfor