Trisomy 21 is a recurrent secondary aber
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Ivan F. Loncarevic; Barbara Roitzheim; Jutta Ritterbach; Susanne Viehmann; Arndt
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Article
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1999
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John Wiley and Sons
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English
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TEL/AML1 gene fusion is the most frequent genetic lesion in pediatric acute lymphoblastic leukemia (ALL). It occurs as a consequence of the cryptic chromosomal translocation t(12;21)(p13;q22). In a cohort of 50 RT-PCR-positive TEL/AML1 patients, karyotype examination by GTG banding and fluorescence