Characterization of ADAM28 as a biomarker of bladder transitional cell carcinomas by urinary proteome analysis
β Scribed by Ming-Hui Yang; Pei-Yu Chu; Sharon Chia-Ju Chen; Tze-Wen Chung; Wen-Cheng Chen; Lia-Beng Tan; Wei-Chih Kan; Hsien-Yi Wang; Shih-Bin Su; Yu-Chang Tyan
- Book ID
- 116302091
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 325 KB
- Volume
- 411
- Category
- Article
- ISSN
- 0006-291X
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There are no reliable serologic tumor markers for transitional cell carcinoma (TCC) of the urinary bladder and noninvasive urine investigations are inadequate. We used fluorescent microsatellite analysis (MSA) to detect serum DNA and urine-sediment DNA alterations in patients with bladder cancer and
## Abstract An antiserum was raised in rabbits by immunization with a human tumor cell line, Tβ24, derived from transitional cell carcinoma (TCC) of the urinary bladder. The specificity of the IgG fraction was assessed by antibodyβdependent cellular cytotoxicity (ADCC), using purified blood lymphoc