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Characterization of Acute Functional Tolerance to the Hypnotic Effects of Ethanol in Mice

โœ Scribed by Igor Ponomarev; John C. Crabbe

Book ID
110086704
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
478 KB
Volume
28
Category
Article
ISSN
0145-6008

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We have developed a precise quantal method for assessing the sensitivity to ethanol in the mouse. Mice placed on a clamped stationary horizontal dowel are scored ataxic or not ataxic depending on whether they are able to remain on the dowel during a 30-s observation period. A threshold blood ethanol