## Abstract Bone‐marrow cells from two leukemic children were co‐cultivated with the canine thymus cell line A 7573. In early passages, C‐type oncornaviruses were released as detected by extracellular reverse transcriptase assay. Co‐cultivation of the infected canine cells with the non‐producing ce
✦ LIBER ✦
Characterization of a type-C virus produced by co-cultures of human leukemic bone-marrow and fetal canine thymus cells
✍ Scribed by R. Guy Smith; Kees Nooter; Peter Bentvelzen; M. Robert-Guroff; K. Harewood; M. S. Reitz; Sin Ai Lee; R. C. Gallo
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- French
- Weight
- 752 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
The putative human helper virus SKA‐21/A204V, isolated by Nooter et aal. in 1977 from human leukemic bone‐marrow cells following co‐culture with normal fetal canine thymus cells, Cf2th, has been characterized with respect to its major viral core protein, reverse transcriptase, and nucleic acid sequences. The results of these analyses show that this virus is not distinguishable from the woolly monkey type‐C virus, SSAV‐1, by the techniques employed.
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John Wiley and Sons
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French
⚖ 694 KB