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Characterization of a trimeric MPER containing HIV-1 gp41 antigen

✍ Scribed by Andreas Hinz; Guy Schoehn; Heribert Quendler; David Lutje Hulsik; Gabi Stiegler; Hermann Katinger; Michael S. Seaman; David Montefiori; Winfried Weissenhorn

Book ID
113947852
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
981 KB
Volume
390
Category
Article
ISSN
0042-6822

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## Abstract A helical, prehairpin trimer covering the majority of the HR1 region of human immunodeficiency virus gp41 was achieved by chemically coupling three identical 51 amino acid peptides. A 1,3,5‐tris(aminomethyl)‐2,4,6‐triethylbenzene pinwheel β€˜cap’ was used to trimerize the peptides by taki