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Characterization of a stable, anchorage-dependent clone obtained from a spontaneously transformed mouse cell line

✍ Scribed by R. Godbout; B. L. Gallie; R. A. Phillips

Book ID
112799011
Publisher
Society for In Vitro Biology
Year
1984
Tongue
English
Weight
765 KB
Volume
20
Category
Article
ISSN
1475-2689

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Characterization of a tumorigenic murine
Characterization of a tumorigenic murine T-lymphoid-cell line spontaneously derived from an IL-2-dependent T-cell line
✍ Varda Mann; Moshe Szyf; Aharon Razin; Evelyne Chriqui-Zeira; Eli Kedar πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 French βš– 593 KB

The establishment of IL-2-independent T-cell lines spontaneously derived from long-term IL-2-dependent cytotoxic T-cell lines is described. Two lines (cloned and uncloned) studied in detail have shown the following characteristics: (1) Permanent loss of IL-2 dependence. (2) Partial or complete loss